“No one tool can catch everything, which is why security experts recommend a layered approach. It’s better to have more than one set of eyes looking at threats from different angles. “I’m sure you’ve heard the old saying ‘jack of all trades, master of none,’” says Samuel Lindsey, Malwarebytes user advocate. “That’s how I see all-in-one security suites; they just can’t detect everything on any given day.”
Your best bet is to use an antivirus program to catch the classic threats and an anti-malware program, like Malwarebytes Anti-Malware Premium, for the newer, more advanced dangers. And you needn’t worry about the impact of running two real-time scanners at the same time on your machine’s performance—most anti-malware software is lightweight, easy-to-run, and designed to work alongside antivirus.”
Source: What’s the difference between antivirus and anti-malware?